Sunscreens Found Not To Protect From Melanoma
Sunscreens Do Not Fully Protect Against The Development Of Melanoma, Mouse Study
The researcher at the Neurosciences Institute, Joint Center of the University
Miguel Hernández (UMH) in Elche and the Higher Council for Scientific Research (CSIC), Berta
López Sánchez-Laorden co-authored a study that concluded that sunscreens do not protect
totally against the development of skin cancer.
The research was recently published in Nature. The study demonstrates that
sunscreen, even with a sun protection factor (SPF) 50, may not fully protect
against the development of melanoma. According to the researcher at the UMH Berta López Sánchez Laorden, sunscreen protects against immediate radiation damage including
sunburn, but the radiation can still penetrate and damage the DNA of cells and
cause cancer. Through the use of genetically modified mice particularly
susceptible to melanoma, the researcher discovered that ultraviolet light
causes mutations in the DNA of melanocytes in a gene called p53. This is one of
the genes considered as guardians of the genome as it is key in detecting and
repairing damage that accumulates in cells, such as the produced by ultraviolet
light, and is a major barrier of the body against cancer.
Several epidemiological studies have shown an association between sun exposure
and the increased risk of melanoma. However, the molecular mechanism that
causes this to happen was not clear. Berta López Sánchez-Laorden is co-author of the work, which has been one of the main projects
carried out during her first postdoctoral, developed in the Institute of Cancer
Research in London and the Cancer Research UK Manchester Institute.
The above story is based on materials provided by Asociación RUVID. Note: Materials may be edited for content and